You can only use an effect if somewhere up the call stack there is a place where that effect will be handled. In Java you need a catch around every throw, even if for runtime exceptions you can skirt around this slightly. In languages with async/await you must decorate a call to an async function with await, and the function you’re calling from must be async. Eventually up the call stack you’ll get to a call that adds the async work to a task queue, executor, or blocks waiting for it to complete. These are all examples of effect handlers for async programming. They provide the scheduling effects that the async code needs in order to run.
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